diff --git a/Makefile.PL b/Makefile.PL
index ed8c0f3..0e0c579 100644
--- a/Makefile.PL
+++ b/Makefile.PL
@@ -236,6 +236,7 @@ if (DEVELOPER_ONLY) {
 
 if ( $^O eq 'cygwin') {
 	push @CC_DEFINE, '-DSQLITE_TEMP_STORE=2';
+	push @CC_DEFINE, '-DTHREADSAFE=0';
 }
 if ( $Config{d_usleep} || $Config{osname} =~ m/linux/ ) {
 	push @CC_DEFINE, '-DHAVE_USLEEP=1';